Peter J Mohler Selected Research

Ion Channels (Ion Channel)

1/2021	Phospho-ablation of cardiac sodium channel Nav1.5 mitigates susceptibility to atrial fibrillation and improves glucose homeostasis under conditions of diet-induced obesity.
1/2021	MicroRNA Biophysically Modulates Cardiac Action Potential by Direct Binding to Ion Channel.
1/2020	Silencing miR-370-3p rescues funny current and sinus node function in heart failure.
1/2020	Abnormal myocardial expression of SAP97 is associated with arrhythmogenic risk.
1/2016	Common human ANK2 variant confers in vivo arrhythmia phenotypes.
1/2015	Alternative paradigms for ion channelopathies: disorders of ion channel membrane trafficking and posttranslational modification.
2/2014	Defective interactions of protein partner with ion channels and transporters as alternative mechanisms of membrane channelopathies.
10/2013	βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells.
10/2012	Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease.
6/2011	Beyond membrane channelopathies: alternative mechanisms underlying complex human disease.

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Peter J Mohler Research Topics

Disease

47	Cardiac Arrhythmias (Arrythmia) 01/2021 - 02/2003
26	Heart Failure 01/2021 - 03/2010
15	Atrial Fibrillation 01/2021 - 09/2011
14	Heart Diseases (Heart Disease) 10/2020 - 07/2006
14	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2020 - 02/2003
14	Myocardial Infarction 01/2017 - 05/2008
13	Fibrosis (Cirrhosis) 01/2021 - 04/2012
11	Cardiovascular Diseases (Cardiovascular Disease) 10/2019 - 10/2008
10	Sick Sinus Syndrome 01/2020 - 05/2005
9	Ankyrin-B-Related Cardiac Arrhythmia 01/2020 - 07/2006
8	Bradycardia 01/2020 - 06/2004
8	Cardiomyopathies (Cardiomyopathy) 01/2020 - 11/2007
7	Channelopathies 01/2020 - 05/2005
7	Ventricular Tachycardia 10/2018 - 07/2006
7	Brugada Syndrome 01/2017 - 12/2004
6	Polymorphic catecholergic ventricular tachycardia 12/2017 - 06/2003
6	Long QT Syndrome 08/2010 - 02/2003
5	Cardiomegaly (Heart Hypertrophy) 12/2018 - 12/2011
5	Infarction (Infarctions) 01/2013 - 09/2008
4	Ischemia 10/2018 - 09/2007
4	Hypertrophy 01/2015 - 12/2009
4	Sudden Death 12/2012 - 06/2004
3	Hypertension (High Blood Pressure) 06/2015 - 02/2010
3	Atrial Remodeling 05/2012 - 09/2008
2	Obesity 01/2021 - 01/2018
2	Constipation 01/2020 - 09/2015
2	Coronary Occlusion 05/2018 - 01/2013
2	Inflammation (Inflammations) 01/2018 - 01/2013
2	Left Ventricular Dysfunction 01/2016 - 06/2015
2	Ataxia (Dyssynergia) 10/2013 - 07/2006
2	Nervous System Diseases (Neurological Disorders) 06/2011 - 11/2009
1	COVID-19 10/2022
1	Infections 10/2022
1	Ventricular Premature Complexes (Premature Ventricular Contraction) 01/2022
1	Body Weight (Weight, Body) 01/2021
1	Myotonic Dystrophy (Dystrophia Myotonica) 01/2020
1	Cardiac Conduction System Disease 01/2020
1	Seizures (Absence Seizure) 01/2020
1	Pulmonary Arterial Hypertension 03/2018
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 09/2017
1	Muscular Dystrophies (Muscular Dystrophy) 09/2017
1	Cardiotoxicity 02/2016

Drug/Important Bio-Agent (IBA)

39	AnkyrinsIBA 01/2020 - 02/2003
32	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2005
24	Ion Channels (Ion Channel)IBA 01/2021 - 02/2003
24	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2021 - 09/2007
10	SpectrinIBA 01/2021 - 10/2013
10	CalciumIBA 01/2020 - 06/2003
9	Calcium-Calmodulin-Dependent Protein KinasesIBA 01/2020 - 09/2007
7	Adrenergic Agents (Adrenergic Drugs)IBA 01/2022 - 11/2011
7	MicroRNAs (MicroRNA)IBA 01/2021 - 04/2007
5	Adenosine (Adenocard)FDA LinkGeneric 10/2020 - 07/2014
4	Messenger RNA (mRNA)IBA 10/2022 - 03/2018
4	SodiumIBA 01/2021 - 04/2012
4	Sodium Channels (Sodium Channel)IBA 01/2021 - 04/2012
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2015 - 05/2012
4	Angiotensin IIIBA 05/2012 - 02/2010
4	Peptides (Polypeptides)IBA 01/2012 - 07/2006
3	Protein Isoforms (Isoforms)IBA 01/2020 - 12/2005
3	Phosphotransferases (Kinase)IBA 12/2018 - 03/2011
3	Calmodulin (Calcium-Dependent Activator Protein)IBA 12/2018 - 03/2011
3	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 11/2018 - 06/2003
3	Pharmaceutical PreparationsIBA 02/2016 - 01/2007
3	Membrane Proteins (Integral Membrane Proteins)IBA 05/2012 - 07/2010
3	Adenosine Triphosphatases (ATPase)IBA 11/2010 - 12/2005
2	Biological ProductsIBA 01/2021 - 01/2013
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2017 - 11/2011
2	Adenosine A1 ReceptorIBA 08/2016 - 07/2014
2	CatecholaminesIBA 06/2016 - 11/2011
2	CalpainIBA 01/2016 - 08/2012
2	Ranolazine FDA Link 09/2015 - 08/2013
2	NADPH Oxidases (NAD(P)H oxidase)IBA 06/2015 - 11/2011
2	Connexin 43 (Connexin43)IBA 03/2013 - 04/2012
2	EnzymesIBA 11/2011 - 06/2011
2	Methionine Sulfoxide ReductasesIBA 11/2011 - 05/2008
2	Adenosine Triphosphate (ATP)IBA 09/2010 - 09/2007
1	N-(2-cyanoethylene)urea (BA 1)IBA 10/2022
1	N-methyl-valyl-amiclenomycin (BA 2)IBA 10/2022
1	VaccinesIBA 10/2022
1	Neutralizing AntibodiesIBA 10/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2020
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2020
1	RNA Splicing FactorsIBA 01/2020
1	IvabradineIBA 01/2019
1	Protein Kinases (Protein Kinase)IBA 12/2018
1	Mexiletine (Mexitil)FDA LinkGeneric 10/2018
1	TubulinIBA 05/2018
1	CytokinesIBA 01/2018
1	DystrophinIBA 09/2017
1	Caffeine (No Doz)FDA LinkGeneric 01/2017
1	zacoprideIBA 01/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2016
1	Dexrazoxane (Zinecard)FDA LinkGeneric 02/2016
1	Endothelin-1 (Endothelin 1)IBA 01/2016

Therapy/Procedure

4	Therapeutics 01/2019 - 07/2011
1	Electrodes (Electrode) 10/2020
1	Intraperitoneal Injections 01/2020
1	Heart Transplantation (Grafting, Heart) 01/2018
1	Heart-Assist Devices 01/2018